Nasal spray: the newest weapon for the fight against Covid-19

A patented medical device with innovative nanotechnology capable of kill the Sars-CoV-2 virus. Italy has started the study. The first results will be available in about four months.

spray nasale covid-19

With the progress of the vaccination campaign and the simultaneous reduction of infections, we are finally seeing the horizon line. However, it is not yet time to claim victory, many virologists and experts are convinced that the COVID-19 it will not leave quite easily. Then, they stay fundamental therapies for the treatment of the disease but above all prevention. Distancing e masks, of course are important, but also many alternative methods, which are being tested in various countries around the world, including Europe and Italy. One of the most curious - and it seems effective too - is it nasal spray anti Covid. Developed by a team of Italians from the Italian-Swiss company Apr Applied Pharma Research sa., which has patented this innovative nanotechnology - called Tehclo- should be available by the end of this year. At the moment, this company has started the trial to evaluate its effectiveness in reducing the viral load in the upper respiratory tract in Covid-19 patients with a mild clinical picture.

Conducting the study, the Hygiene Unit ofIrccs San Martino Polyclinic Hospital in Genoa, coordinated by Prof. Giancarlo Icardi. The preliminary results will be available in about four months.

How does the test work?

The spray, which must be inhaled three to five times a day, works as a real "washing", which irrigates, hydrates and cleans the nasal mucous membranes.

Contains an aqueous solution of 0.005% hypochlorous acid, an antimicrobial substance also produced by the cells of our immune system capable of mechanically removing and killing viruses and bacteria in less than a minute, including Sars-CoV-2 even in its various mutations. All without irritating the mucous nose and throat membranes.

These results were confirmed from the analyzes conducted last June by theInstitute for Antiviral Research of Utah State University (the report was recently published in the Official Journal of the European Society of Otolaryngology).  

The spray can be stored for two years at room temperature, between 5 and 25 ° C, without particular precautions. 

Clearly, should be used in addition to standard therapies. "Thanks to both mechanical effect of washing and antimicrobial efficacy of hypochlorous acid, it could in fact reduce the contagiousness of patients, prevent the onset of more serious symptoms and improve the course of the disease in the early phase, also reducing the likelihood of transmission of the virus also to other subjects ”, underlined Prof. Giancarlo Icardi. "If Sars-CoV-2 is present in smaller quantities in the upper respiratory tract, in fact, the probability that it can go down into the lower airways, damaging the lungs, is lowered, as well as the risk of local lesions to the olfactory nerve tracts, responsible for the loss of smell. related to Covid-19. The spray, therefore - he concluded - if used in the initial stages of infection or in case of exposure to the risk of infection, could decrease the probability of contagion, clinical worsening and transmissibility of the infection ".

“From the preliminary statistic data, we know that at the EU level there will be a good part of the population who will not get vaccinated, it is estimated that 20-30% is due to hesitating or against it or because it has clinical conditions that do not allow it. With the spray, we aim at these people ", explained to Adnkronos Salute Paolo Galfetti, CEO of Apr. “If the trial started at the Irccs San Martino hospital in Genoa is successful - he continued - by the end of the year, we will have the spray on the market. The target, besides helping those who are not immunized, is being able to provide a valid medical device even we still do not have absolute scientific proofs about the potential contagiousness of vaccinated people and how long the vaccination coverage will last. In case we would have then a nasal spray that will help us against the COVID-19, let's think for example of closed environments, means of transport or theatres and cinemas. There are good premises and the preliminary data lead us to be very optimistic about the success of the spray and its effectiveness against Covid variants ".

The spray can be especially useful in crowded and high-risk environments, such as public transport and shopping centres, acting as a real “barrier”. One more tool, easy to use and suitable for everyone, to boost the return back to normal. 

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